Aim & Objectives: The correlation of Cannabis user groups with duration of one-month, one-year and five year (Both diabetic and non-diabetic groups) with serum Vitamin C level and serum vitamin E level.Research Design and Methods: In a cross-sectional, case-control study, we studied cannabis user 55 and 50 cannabis non-user, male-subjects aged between 25 and 65 years. Fasting blood samples were obtained from 55 diabetic male subjects and 50 healthy control subjects. Blood samples were withdrawn who were taking 5 to 10 gm of cannabis per day and analyzed for Antioxidant serum Vitamin C and serum vitamin E by standard technique using UV-Spectrophotometer. Results: serum Vitamin C and serum vitamin E were measured and the results were compared with those of controls. Antioxidants levels were found to be significantly higher in diabetic and non-diabetic subjects using cannabis 5 to 10 gm per day for the last one month, one year and five years when compare with normal control and diabetic control subjects(p<0.01).Conclusion: Study shows a significant increased in Vitamin C and serum vitamin E level recorded diabetic patients and non diabetic groups using cannabis for the last one year and five year as well as in the whole group as compared to that of normal control. It might be possible that either cannabis may enhanced the insulin release or increase the penetration of sugar into the cells and might be due to antioxidant activity of cannabis.
Diabetes Mellitus, Cannabis sativa, Antioxidants (Vitamin C & E)
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